PEG-mimetic peptoid reduces protein fouling of polysulfone hollow fibers

详细信息    查看全文

• 作者：Neda Mahmoudi^a ; Lauren Reed^a ; Alex Moix^a ; Nawaf Alshammari^b ; Jamie Hestekin^a ; Shannon L. Servoss^a ; ^{sservoss@uark.edu}
• 关键词：Biofouling ; Peptoid ; Polysulfone ; Hollow fiber membrane ; Biocompatibility
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：149
• 期：Complete
• 页码：23-29
• 全文大小：1271 K
• 卷排序：149

文摘

Polysulfone hollow fiber membranes are modified with a peptoid (NMEG5) using polydopamine. The addition of peptoid to the fibers increases the hydrophilicity of the fibers by 74%. Peptoid-modified fibers have significantly decreased protein fouling with bovine serum albumin, lysozyme, and fibrinogen. Peptoid-modified fibers show the lowest amount of fibrinogen adsorption compared to other published low fouling membranes.