Use of von Frey filaments to assess nociceptive sensitization in the hornworm, Manduca sexta
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- 作者：Marissa Zubia McMackina ; mzmcmackin@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Matthew R. Lewinb ; mlewin@calacademy.org" class="auth_mail" title="E-mail the corresponding author ; Dennis R. Tabuenaa ; dennis.r.tabuena2@gmail.com" class="auth_mail" title="E-mail the corresponding author ; F. Eric Arreolaa ; arreola.eric85@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Christopher Moffatta ; moffatt@sfsu.edu" class="auth_mail" title="E-mail the corresponding author ; Megumi Fusea ; fuse@sfsu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Defensive strike response ; Larva ; Von Frey filaments ; SUDO method ; Up-and-down method ; Insect
- 刊名：Journal of Neuroscience Methods
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：257
- 期：Complete
- 页码：139-146
- 全文大小：783 K
文摘
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Von Frey filaments were used to quantify the defensive strike response in M. sexta.
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The first response, up-and-down and SUDO methods were assessed and compared.
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All 3 methods measured changes in threshold sensitivity after a noxious pinch.
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Nociceptive sensitization after the pinch was determined to last 19 h.