Defectos de cierre orofaciales: paladar hendido y labio leporino. Una revisi¨®n bibliogr¨¢fica
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- 作者：G.H. D¨ªaz Casado ; G.J. D¨ªaz Gr¨¢valos
- 关键词：Labio leporino ; Fisura del paladar ; Epidemiologí ; a ; Factores de riesgo ; Etiologí ; a ; Medio ambiente y salud pú ; blica
- 刊名：SEMERGEN - Medicina de Familia
- 出版年：2013
- 出版时间：July-August, 2013
- 年：2013
- 卷：39
- 期：5
- 页码：267-271
- 全文大小：265 K
文摘
Orofacial clefts are a common problem that can lead to significant healthcare use and costs, as well as suffering on the part of the affected individuals and families. There are several theories explaining their origin, but some of the findings are inconsistent. The most accepted theories involve a major genetic basis that could be modified by the presence of external agents. Understanding the underlying causes could help to prevent its occurrence, an area in which the family physician can play an important role.