Giant bulla formation in the lung because of a check-valve mechanism

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• 作者：Aya Hirata ; MD^a ; ^{jkhwq282@yahoo.co.jp} ; Takeshi Saraya ; M.D ; PhD^a ; ^{sara@yd5.so-net.ne.jp} ; Nobuaki Arai ; M.D^b ; ^{ishaninare@mail.goo.ne.jp} ; Shin Karita ; M.D ; PhD^b ; Riken Kawachi ; M.D ; PhD^b ; ^{rkawachi2@gmail.com} ; Hidefumi Takei ; M.D ; PhD^b ; ^{htakei@ks.kyorin-u.ac.jp} ; Kosuke Ohkuma ; M.D^a ; ^{kobu0805@gmail.com} ; Manabu Ishida ; M.D^a ; ^{matsu.manabu@gmail.com} ; Masachika Fujiwara ; M.D ; PhD^c ; ^{masachi@ks.kyorin-u.ac.jp} ; Hajime Takizawa ; MD ; PhD^a ; ^{hajime@ks.kyorin-u.ac.jp}
• 关键词：Bulla formation ; Pneumothorax ; Organizing pneumonia ; Cryptogenic organizing pneumonia ; Check-valve mechanism
• 刊名：Respiratory Investigation
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：55
• 期：1
• 页码：63-68
• 全文大小：2393 K
• 卷排序：55

文摘

The pathogenesis of bulla formation has not yet been demonstrated in pathologic examinations or through direct visualization during thoracotomy or thoracoscopic surgery. We present two cases of giant bulla formation after pneumothorax because of cryptogenic organizing pneumonia and lung abscess. The case findings suggested that the pathogenesis was attributable to a check-valve mechanism, secondary to bronchiolitis obliterans, or the presence of an obstructing air leakage due to a lung fistula. The lung fistula had been covered by inflammatory membranes consisting of blood and/or fibrous precipitates with detached visceral pleura.