Sensitivity of CT angiography, T2-weighted MRI, and magnetic resonance angiography in detecting cerebral arteriovenous malformations and associated aneurysms

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• 作者：Bradley A. Gross ; Kai U. Frerichs ; Rose Du
• 关键词：Arteriovenous malformation ; AVM ; Hemorrhage ; Aneurysm ; CTA ; MRI ; MRA
• 刊名：Journal of Clinical Neuroscience
• 出版年：2012
• 出版时间：August, 2012
• 年：2012
• 卷：19
• 期：8
• 页码：1093-1095
• 全文大小：293 K

文摘

An increasing number of patients with arteriovenous malformations (AVM) are being screened with expedient, safe, and non-invasive methods such as computed tomography angiography (CTA), MRI, and magnetic resonance angiography (MRA). Only a paucity of small series have examined the sensitivity of these modalities in detecting AVMs. In this study, we reviewed 125 patients with AVMs, demonstrating overall sensitivities of 90 % for CTA, 89 % for T2-weighted MRI, and 74 % for MRA. The greater sensitivity of CTA in detecting AVMs compared to MRA did meet statistical significance (pub>CTA, MRAub> = 0.036). For unruptured AVMs, the sensitivities were 96 % , 97 % and 71 % (pub>CTA, MRAub> = 0.043) and for ruptured AVMs, they were 87 % , 83 % and 77 % , respectively. The sensitivity was 100 % for both CTA and T2-weighted MRI for AVMs larger than 3 cm. Importantly, associated aneurysms were best detected via CTA, with a sensitivity of 88 % , as compared to 29 % for MRI and 27 % for MRA (pub>CTA, MRAub> = 1.2 ¡Á 10up>?6up>), with the greatest distinction occurring within the subgroup of intranidal aneurysms with a sensitivity of 83 % for CTA compared to 0 % for both MRI and MRA (pub>CTA, MRAub> = 0.005).