Use of FTIR spectroscopy and PCA-LDC analysis to identify cancerous lesions within the human colon

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• 作者：E. Kaznowska^a ; ^b ; ¹ ; J. Depciuch^c ; ¹ ; ^{joannadepciuch@gmail.com} ; K. Szmuc^d ; J. Cebulski^d
• 关键词：FTIR ; Colorectal cancer ; Chemotherapy ; PCA-LDC
• 刊名：Journal of Pharmaceutical and Biomedical Analysis
• 出版年：2017
• 出版时间：5 February 2017
• 年：2017
• 卷：134
• 期：Complete
• 页码：259-268
• 全文大小：2585 K
• 卷排序：134

文摘

FTIR is a sensitive distribution indicator for the main biochemical compounds of healthy and cancerous colon tissue. Cancerogenesis caused changes in spectrum representing the vibration of nucleic acids, protein and lipid functional groups. Post-chemotherapy colon tissues FTIR spectrum was similar with healthy colon tissues.