Impaired acquisition of conditioned taste aversion memory induced by isoflurane is accompanied with calcineurin activation and Egr-1 down-regulation in amygdala in rats
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- 作者：Sensen Wang1 ; Lei Zhuang1 ; Xiaoxuan Yang ; Qiang Li ; Qingsheng Xue ; Yan Luo ; Fujun Zhang ; Buwei Yu ; yubuwei_2015@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Isoflurane ; Conditioned taste aversion ; Calcineurin ; Early growth response 1 ; ERK
- 刊名：Neuroscience Letters
- 出版年：2015
- 出版时间：21 October 2015
- 年：2015
- 卷：607
- 期：Complete
- 页码：114-119
- 全文大小：1223 K
文摘
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Isoflurane exposure disrupted the establishment of aversion memory in rats.
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Calcineurin activation and Egr-1 down-regulation may contribute to the isoflurane induced impairment of CTA memory acquisition.
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Isoflurane preconditioning may prevent negative emotional memory of traumatic events.