Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen
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文摘

T. gondii GRA2 and GRA6 shape tubules of the intravacuolar network (IVN)

GRA6 association with PV membranes promotes MHC I antigen presentation

GRA6 binding to IVN limits its MHC I antigen presentation in vitro and in vivo

Membranes of T. gondii IVN may play a role in immune modulation

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