Postradiofrequency ablation inflammatory pseudotumor associated with pulmonary venoocclusive disease: case report and review of the literature

详细信息    查看全文

• 作者：Alex ; ra E. Kovach ; George Z. Cheng ; Colleen L. Channick ; Richard N. Channick ; Ashok Muniappan ; Henning A. Gaissert ; Richard L. Kradin
• 关键词：Pulmonary vein stenosis ; Veno-occlusive disease ; Radiofrequency ablation ; Inflammatory pseudotumor
• 刊名：Annals of Diagnostic Pathology
• 出版年：2013
• 出版时间：October, 2013
• 年：2013
• 卷：17
• 期：5
• 页码：466-469
• 全文大小：1755 K

文摘

Radiofrequency ablation of pulmonary veins is a common therapeutic intervention for atrial fibrillation. Pulmonary vein stenosis and venoocclusive disease are recognized complications, but the spectrum of pathologies postablation have not been previously reviewed. A recent case at our hospital showed a left hilar soft tissue mass in association with superior pulmonary vein stenosis in a patient 4 years postablation. On resection, this proved to be an inflammatory pseudotumor composed of myofibroblasts in an organizing pneumonia-type pattern with adjacent dendriform ossifications. Pulmonary venoocclusive change was a prominent feature. Literature on the histopathology of postradiofrequency ablation complications is limited. The severity of vascular pathology appears to increase with the postablation interval. Although pulmonary vascular changes are the most common late finding, fibroinflammatory changes including pulmonary pseudotumor formation, attributable to thermal injury, should be considered in the differential diagnosis of these cases.