The Bactericidal Lectin RegIIIβ Prolongs Gut Colonization and Enteropathy in the Streptomycin Mouse Model for Salmonella Diarrhea

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• 作者：Tsuyoshi Miki¹ ; ³ ; ^{mikit@pharm.kitasato-u.ac.jp} ; Ryosuke Goto¹ ; Mayuka Fujimoto¹ ; Nobuhiko Okada¹ ; Wolf-Dietrich Hardt²
• 关键词：RegIIIβ ; Salmonella diarrhea ; gut colonization ; enteropathy ; Bacteroides spp. ; vitamin B6
• 刊名：Cell Host & Microbe
• 出版年：2017
• 出版时间：8 February 2017
• 年：2017
• 卷：21
• 期：2
• 页码：195-207
• 全文大小：2378 K
• 卷排序：21

文摘

RegIIIβ prolongs the duration of Salmonella diarrhea in the streptomycin mouse model RegIIIβ alters the composition of the gut microbiota and colonic metabolism Supplementation with Bacteroides acidifaciens promotes remission of Salmonella diarrhea The gut microbiota-derived vitamin B6 may be a key factor for Salmonella gut infection