Effect of a water-rich diet on adrenal zona glomerulosa in Gerbillus tarabuli

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• 作者：Leila Saadi^a ; ^{saadileila4@gmail.com} ; Nemcha Lebaili^b
• 关键词：Gerbillus tarabuli ; Perturbation ; Water-rich diet ; Adrenal zona glomerulosa ; Aldosterone
• 刊名：Comptes Rendus Biologies
• 出版年：2012
• 出版时间：February 2012
• 年：2012
• 卷：335
• 期：2
• 页码：96-102
• 全文大小：1354 K

文摘

The objective of this work is to evaluate the aldosterone level and to study the gerbil adrenal zona glomerulosa morphology in the presence of an important water diet content during seven days. Thirty adult gerbils, Gerbilus tarabuli, were randomly assigned to two watering regimes, with fifteen gerbils per group. The first group was the control and the second group was exposed to a water-rich diet during seven days. Thin sections of the adrenal glands were observed in photonic and electron microscopy. Their blood was sampled and analyzed for aldosterone, electrolyte concentrations and hematocrit. Urine was collected after 24 hours. A water-rich diet decreased the body weight but increased the hematocrit, total protein, aldosterone concentration and urine volume. In electronic microscopy, the adrenal zona glomerulosa cells present a decrease in lipid compartment and Golgi apparatus zone development. The blood electrolyte concentrations were not changed significantly. These findings indicate that the water-rich diet exerts a potent stimulatory effect on aldosterone secretion by the gerbil adrenal zona glomerulosa through plasma volume perturbation.