文摘
Glucagon-like peptide-1(9-36), the cleaved form of GLP-1, is active on human adipose stem cells (ASC) in vitro. GLP-1(9-36) inhibits ASC proliferation and adipogenesis, and induces cell apoptosis. These effects are not inhibited by exendin(9-39), suggesting a mechanism of action different from the classical GLP-1R.