Two new peroxy fatty acids with antibacterial activity from Ophioglossum thermale Kom

详细信息    查看全文

• 作者：Jian-Wei Dong¹ ; Le Cai¹ ; Xue-Jiao Li ; Li Peng ; Yun Xing ; Rui-Feng Mei ; Jia-Peng Wang ; Zhong-Tao Ding ; ^{ztding@ynu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Ophioglossum thermale Kom. ; Thermalic acid A ; Thermalic acid B ; Peroxy fatty acid ; Antibacterial activity
• 刊名：Fitoterapia
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：109
• 期：Complete
• 页码：212-216
• 全文大小：791 K

文摘

Two new peroxy fatty acids, thermalic acids A (1) and B (2), together with eight known compounds, (3β)-methyl-3-hydroxy-urs-11-en-28 oate (3), luteolin (4), quercetin (5), 3-methoxyquercetin (6), ophioglonol (7), ophioglonol 4′-O-α-D-glucopyranoside (8), pedunculosumoside B (9), syringol (10), were isolated from the herba of Ophioglossum thermale Kom. The structures of 1 and 2 were identified by HRESIMS, EIMS, 1D and 2D NMR, and electronic circular dichroism (ECD) spectra. Both two acids exhibited potential antibacterial activities against Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. This is the first report of peroxy fatty acids isolated from herbaceous plants of Ophioglossaceae.