Two new flavonoid glycosides from Iris tectorum
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- 作者：Chun-Lei Zhanga ; b ; Yan Wanga ; Yan-Fei Liua ; Dong Lianga ; Zhi-You Haoa ; Huan Luoa ; Ruo-Yun Chena ; Zheng-Yu Caob ; De-Quan Yua ; dqyu@imm.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Iris tectorum ; Flavonoid glycosides ; Aldose reductase
- 刊名：Phytochemistry Letters
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：15
- 期：Complete
- 页码：63-65
- 全文大小：384 K
文摘
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Two new and two known flavonoid glycosides were isolated from Iris tectorum.
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The linkage pattern of the rhamnose substituent at C-5 was not common in naturally occurring flavonoid glycosides.
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Their structures were elucidated by spectroscopic analysis and chemical evidence.
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All isolates were evaluated for their inhibitory activity against aldose reductase.
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Compound 1 showed moderate inhibitory activity, with IC50 values of 1.63 μM.