Phytosteroids beyond estrogens: Regulators of reproductive and endocrine function in natural products

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• 作者：Matthew Dean^a ; Brian T. Murphy^a ; Joanna E. Burdette^a ; ^{joannab@uic.edu}
• 关键词：Phytosteroid ; Herbal supplement ; Progestin ; Androgen ; Corticoid
• 刊名：Molecular and Cellular Endocrinology
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：442
• 期：Complete
• 页码：98-105
• 全文大小：641 K
• 卷排序：442

文摘

Botanicals contain phytosteroids that bind non-estrogen steroid receptors. Kaempferol, apigenin, and genistein bind progesterone and androgen receptors. Ginsenoside Rf and glycyrrhetinic acid interact with corticoid receptors. Compound A is a novel selective glucocorticoid, based on a phytosteroid. Characterization of phytosteroids will help elucidate their safe and effective use.