Overexpression of heat shock GroEL stress protein in leptospiral biofilm

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• 作者：K. Vinod Kumar^a ; Chandan Lall^a ; R. Vimal Raj^a ; K. Vedhagiri^b ; C. Kartick^a ; P. Surya^a ; K. Natarajaseenivasan^c ; P. Vijayachari^a ; ^{pblicmr@sancharnet.in}
• 关键词：Biofilm ; Leptospira ; Hsp ; Planktonic ; GroEL
• 刊名：Microbial Pathogenesis
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：102
• 期：Complete
• 页码：8-11
• 全文大小：530 K
• 卷排序：102

文摘

Biofilm formation in Leptospires is a new area of study and its molecular mechanism has not been fully explored yet. This study demonstrate the over expression of a stress protein associated with the Leptospira biofilm formation. GroEL is conserved, highly immunogenic and a prominent stress response protein among Leptospira spp. This study will help in understanding the mechanisms of biofilm formation in pathogenic Leptospira.