Pain reduction and functional improvement can be noticed after PRP use in distal radius fracture.
A randomized trial study was designed with 30 patients who had intra-articular distal radius fractures (Frykman types 3, 4, 7, 8). Closed reduction and percutaneous pinning under guide of fluoroscopy were done for them. Fifteen cases received intra-articular autologus PRP. Patients were followed for 3 and 6 months and “patient rated wrist evaluation” (PRWE) questionnaire was completed and range of motion of the wrist was measured.
The mean of pain score and the score of specific and usual activities at 3 months follow-up in the case group and in the control group were (8.33 versus 19.67), (10.66 versus 26.8), and (6.2 versus 13.4), respectively. The mean of pain score and score of specific and usual activities at 6 months follow-up in the case group and in the control group were (3.6 versus 12), (3 versus 15.7), and (1.2 versus 6.8), respectively. The case group was significantly different from the control group. The mean of loss of flexion and extension of the wrist at 3 months follow-up in the case group was significantly different from the control group as well.
PRP may have significant effect on reduction of pain and amount of difficulty in functions including specific and usual activities after intra-articular distal radius fractures.
Level III, therapeutic trial.