Solvent toxicity to amphibian embryos and larvae

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• 作者：Olivier Marquis ; Annie Millery ; Sylvie Guittonneau and Claude Miaud
• 关键词：Organic micropollutants ; Toxicity ; Mortality ; Rana temporaria
• 刊名：Chemosphere
• 出版年：2006
• 出版时间：May 2006
• 年：2006
• 卷：63
• 期：5
• 页码：889-892
• 全文大小：94 K

文摘

Organic micropollutants are often damaging for aquatic organisms. Being usually hydrophobic compounds, they are often dissolved in an organic co-solvent which increases their solubility in water. The aim of this study was to study the toxicity of various solvents on embryos (protected or not by jelly coat) and on tadpoles of the common frog (Rana temporaria). Tested solvents were methanol (MeOH), methylene chloride (CH₂Cl₂), dimethyl sulfoxyde (DMSO), acetone (Ac) and ethanol (EtOH). Embryos exhibited higher mortality rates than tadpoles. Embryos with jelly were more sensitive to high concentration of solvents than embryos without jelly (except for acetone). According to these results, Ac, DMSO and CH₂Cl₂ can be used as co-solvents in water to help the dissolution of micropollutants at concentration equal to or lower than 0.001 ml/l for frog embryos, and EtOH, Ac and CH₂Cl₂ at concentration equal to or lower than 0.01 ml/l for Rana temporaria tadpoles.