Survey of antibiotic use of individuals visiting public healthcare facilities in Indonesia

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• 作者：Usman Hadi ; D. Offra Duerink ; Endang Sri Lestari ; Nico J. Nagelkerke ; Susanne Werter ; Monique Keuter ; Eddy Suw ; ojo ; Eddy Rahardjo ; Peterhans van den Broek ; Inge C. Gyssens
• 关键词：Antibiotic policy ; Antimicrobial agents ; Resistance ; Community ; Self-medication
• 刊名：International Journal of Infectious Diseases
• 出版年：2008
• 出版时间：November 2008
• 年：2008
• 卷：12
• 期：6
• 页码：622-629
• 全文大小：172 K

文摘

class=""h3"">Summary

class=""h4"">Objectives

To estimate the antibiotic use of individuals visiting public healthcare facilities in Indonesia and to identify determinants of use against a background of high resistance rates.

class=""h4"">Methods

Patients on admission to hospital (group A), visiting a primary health center (group B), and healthy relatives (group C) were included in the study. A questionnaire on demographic, socioeconomic, and healthcare-related items including health complaints and consumption of antibiotics was used. Logistic regression was performed to determine the co-variables of antibiotic use.

class=""h4"">Results

Of 2996 individuals interviewed, 486 (16 % ) had taken an antibiotic. Compared to group C (7 % consumption), groups B and A exhibited a three-fold and four-fold higher use of antibiotics, respectively. Respiratory (80 % ) and gastrointestinal (13 % ) symptoms were most frequent. Aminopenicillins and tetracyclines accounted for 80 % of the prescribed antibiotics. Similar antibiotics were self-medicated (17 % of users). Age less than 18 years and health insurance were independent determinants of antibiotic use. Urban provenance, being adult, male, and having no health insurance were independent determinants of self-medication.

class=""h4"">Conclusions

In addition to health complaints, other factors determined antibiotic consumption. In view of the likely viral origin of respiratory complaints and the resistance of intestinal pathogens, most antibiotic use was probably unnecessary or ineffective. Future interventions should be directed towards healthcare providers.