Antimicrobial peptide, hdMolluscidin, purified from the gill of the abalone, Haliotis discus
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- 作者：Jung-Kil Seoa ; 1 ; jungkileun@kunsan.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Hye-Jin Gob ; 1 ; Chan-Hee Kimb ; Bo-Hye Namc ; Nam Gyu Parkb ; ngpark@pknu.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antimicrobial activity ; Innate immunity ; Abalone ; Haliotis discus ; hdMolluscidin
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：52
- 期：Complete
- 页码：289-297
- 全文大小：1599 K
文摘
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A novel antimicrobial peptide, hdMolluscidin, was isolated and cloned from the gill of the abalone, Haliotis discus.
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hdMolluscidin consists of 46 amino acids with 4767.2 Da molecular mass as a linear form.
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hdMolluscidin was constitutively expressed as a mature form in the gill tissue.
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hdMolluscidin showed broad and potent antimicrobial spectrum without hemolysis and may target intracellular components.
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hdMolluscidin play an important role in the innate defenses of the abalone.