文摘
Background and objective
The aim of our study was to identify the rate of diabetic patients treated for hypothyroidism and compare them with a group without type 2 diabetes mellitus (T2DM).Patients and methods
<p>We reviewed the computerized clinical records of 5161 patients. We identified diabetic patients treated with l-thyroxine. We compared the prevalence of PH with those patients under treatment with levothyroxine without T2DM. We excluded patients with a thyroid neoplasia, thyroid surgery, panhypopituitarism, or surgical complications of multinodular goiter or a thyroid nodule. Subclinical hypothyroidism was not considered.Results
<p>We included 1848 adult patients with T2DM in the study group, 58 % women and 42 % men. For the control group, we included 3313 non-diabetic patients, 55 % women and 45 % men. The mean age in the study group was 52 ¡À 7 years, and 47 ¡À 4 years in the control group (p < .001). The rate of hypothyroidism in the study group was 5.7 % , and in the control group 1.8 % (odds ratio of 3.45; 95 % confidence interval 2.51-4.79) (p < .001).Conclusion
<p>A strong association between T2DM and hypothyroidism was found. We recommend a thyroid profile in all patients with T2DM, similar to the recommendation in type 1 diabetes mellitus.