Fluoride gel supplemented with sodium hexametaphosphate reduces enamel erosive wear in situ

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• 作者：J.M. Conceiç ; ã ; o^a ; A.C.B. Delbem^a ; M. Danelon^a ; D.M. da Camara^a ; A. Wiegand^b ; J.P. Pessan^a ; ^{jpessan@foa.unesp.br" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Dental erosion ; Dental abrasion ; Topical fluorides ; Dental enamel ; Sodium hexametaphosphate
• 刊名：Journal of Dentistry
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：43
• 期：10
• 页码：1255-1260
• 全文大小：512 K

文摘

This study evaluated the effect of fluoride gels, supplemented or not with sodium hexametaphosphate (HMP), on enamel erosive wear in situ.

Methods

Twelve healthy volunteers wore palatal appliances containing four bovine enamel discs. Subjects were randomly allocated into four experimental phases (double-blind, crossover protocol) according to the gels: Placebo (no fluoride or HMP), 1% NaF, 2% NaF, and 1% NaF + 9% HMP. Enamel discs were selected after polishing and surface hardness analysis, and treated only once with the respective gels prior to each experimental phase. Erosion (ERO) was performed by extra-oral immersion of the appliance in 0.05 M citric acid, pH 3.2 (four times/day, five minutes each, 5 days). Additional abrasion (ERO + ABR) was produced on only two discs by toothbrushing with fluoridated dentifrice after ERO (four times/day, 30 s, 5 days). The specimens were submitted to profilometry and hardness analysis. The results were analyzed by two-way ANOVA and the Student–Newman–Keuls test (p < 0.05).

Results

The 1% NaF + 9% HMP gel promoted significantly lower enamel wear for ERO compared to the other groups, being statistically lower than 1% NaF and Placebo for ERO + ABR. Similarly, the lowest values of integrated lesion area were found for 1% NaF + 9% HMP and 2% NaF, respectively, for ERO and ERO + ABR.

Conclusion

The addition of HMP to the 1% NaF gel promoted greater protective effect against ERO and ERO + ABR compared to the 1% NaF gel, achieving similar protective levels to those seen for the 2% NaF gel.

Clinical significance

Gel containing 1% NaF + 9% HMP showed a high anti-erosive potential, being a safer alternative when compared to a conventional 2% NaF gel.