Krypton laser-induced photothrombotic distal middle cerebral artery occlusion without craniectomy in mice

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• 作者：Sugimori ; Hiroshi ; Yao ; Hiroshi ; Ooboshi ; Hiroaki ; Ibayashi ; Setsuro ; Iida ; Mitsuo
• 关键词：J ; Disorders of the nervous system ; Ischemia ; Mouse ; Cerebral ischemia ; Focal ; Photochemistry
• 刊名：Brain Research Protocols
• 出版年：2004
• 出版时间：August, 2004
• 年：2004
• 卷：13
• 期：3
• 页码：189-196
• 全文大小：329 K

文摘

Recent advances in genetical engineering of the mouse have highlighted the importance of reproducible and less invasive models of cerebral ischemia in mice. In this paper, we developed minimally invasive and reproducible model of distal middle cerebral artery (MCA) occlusion in mice using krypton (Kr) laser-induced photothrombosis.