Cerebral Venous Thrombosis Associated With Iron Deficiency Anemia

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• 作者：Toshiyasu Ogata ; Masahiro Kamouchi ; Takanari Kitazono ; Junya Kuroda ; Hiroaki Ooboshi ; Tadahisa Shono ; Takato Morioka ; Setsuro Ibayashi ; Tomio Sasaki ; Mitsuo Iida
• 关键词：Cerebral venous thrombosis ; coagulation ; anemia
• 刊名：Journal of Stroke and Cerebrovascular Diseases
• 出版年：2008
• 出版时间：November-December 2008
• 年：2008
• 卷：17
• 期：6
• 页码：426-428
• 全文大小：148 K

文摘

A 55-year-old man presented with generalized seizures and postictal left hemiparesis. Computed tomography scanning of his head showed a low density area in the right frontal lobe. Cerebral angiography demonstrated a partial defect in the superior sagittal sinus and cortical veins, indicating the presence of cerebral venous thrombosis. He had bleeding from a peptic ulcer and the laboratory data revealed iron deficiency anemia concomitant with an elevation of D-dimer and thrombin-antithrombin III complex (TAT). After the anemia resolved with the treatment of the peptic ulcer and iron supplementation, the TAT and D-dimer levels were normalized, and the occluded veins were recanalized. In a cerebral venous thrombosis associated with iron deficiency anemia, treatment for the anemia may improve hypercoagulable state without antithrombotic therapy, although the long-term monitoring of TAT and D-dimer levels is required.