Comparison of the Liaison® Calprotectin kit with a well established point of care test (Quantum Blue — Bühlmann-Alere®) in terms of analytical performances and ability to detect relapses amongst a Crohn population in follow-up
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- 作者：Quentin Delefortriea ; quentin.delefortrie@uclouvain.be" class="auth_mail" title="E-mail the corresponding author ; Patricia Schatta ; Alexandre Grimmelpreza ; Patrick Gohya ; Didier Deltoura ; Geneviè ; ve Collardb ; Patrick Vankerkhovena
- 关键词：Calprotectin ; Liaison® ; Calprotectin ; Quantum Blue® ; Inflammatory bowel disease ; Crohn's disease relapse screening ; Crohn's disease follow-up
- 刊名：Clinical Biochemistry
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：49
- 期：3
- 页码：268-273
- 全文大小：472 K
文摘
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A newly developed kit for calprotectin measurement (Liaison® Calprotectin) was evaluated and compared to a well established and validated point of care test (Quantum Blue® - Alere-Bülhmann®)
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All three procedures gave significantly different calprotectin levels (P = 0.05)
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Optimal cut-offs (defined as the maximum sum of sensitivity and specificity) for detecting relapse amongst a Crohn's population in follow-up and their associated negative predictive values were also calculated