Pulpal Tissue Inflammatory Reactions after Experimental Pulpal Exposure in Mice

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• 作者：Ying He ; DDS^&lowast ; ; Youhua Gan ; DDS^&dagger ; ; Jiajian Lu ; DDS^&lowast ; ; Qiong Feng ; DDS^&lowast ; ; Haiyan Wang ; DDS^&lowast ; ; Hongbing Guan ; PhD^&lowast ; ; Qianzhou Jiang ; DDS ; PhD^&lowast ; ; ^{jqianzhou@126.com}
• 关键词：Animal model ; histomorphologic evaluation ; pulpal inflammation
• 刊名：Journal of Endodontics
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：43
• 期：1
• 页码：90-95
• 全文大小：1514 K
• 卷排序：43

文摘

A convenient model for studying the pathogenesis of pulpitis is created. As the duration of pulpal exposure increases, inflammatory reaction is exacerbated. The expression levels of inflammatory cytokines increased over 72 hours. There was a high rate of inflammatory cytokine expression at 6 and 12 hours. Mouse pulpitis progresses rapidly, with dramatic changes evident in just a few hours.