Synthesis of quinazolin-4(3H)-ones and 1,2-dihydroquinazolin-4(3H)-ones with the aid of a low-valent titanium reagent

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• 作者：Shi ; Daqing ; Rong ; Liangce ; Wang ; Juxian ; Zhuang ; Qiya ; Wang ; Xiangshan ; Hu ; Hongwen
• 刊名：Tetrahedron Letters
• 出版年：2003
• 出版时间：April 7, 2003
• 年：2003
• 卷：44
• 期：15
• 页码：3199-3201
• 全文大小：127 K

文摘

A short and facile synthesis of a series of quinazolin-4(3H)-ones and 1,2-dihydroquinazolin-4(3H)-ones was accomplished in good yields via the novel reductive cyclization of o-nitrobenzamides and triethyl orthoformate, aldehydes or ketones promoted by TiCl₄/Zn.