Background: This review presents an overview of interventional revascularization procedures of the internal thoracic artery after prior implantation as a coronary-artery bypass graft. Methods: Our search was concentrated on the MEDLINE-database to identify all articles on internal thoracic artery-graft–angioplasties and reoperation after internal thoracic artery bypass grafting published between 1968 and 2000. Results: Surgical revascularization and reoperation were reported in five papers including a total of 785 patients. The overall mortality of these patients was 4.2 % . The presence of a patent internal thoracic artery-graft at the time of reoperation was not a risk factor for higher morbidity and mortality. Revascularization with percutaneous transluminal coronary angioplasty of the internal thoracic artery or the native left anterior descending artery via the internal thoracic artery-graft used as a conduit was performed in 327 patients. The primary success rate was 87 % , the angiographically assessed rate of restenosis was 30 % and the rate of complications approximately 1 % . Conclusions: Inspite of technical problems the percutaneous transluminal coronary angioplasty in or via internal thoracic artery-graft presents a safe and feasible option to be recognized before a potential reoperation.