MAT2B promotes adipogenesis by modulating SAMe levels and activating AKT/ERK pathway during porcine intramuscular preadipocyte differentiation
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- 作者：Cunzhen Zhao ; Xiaochang Chen ; Wenjing Wu ; Wusu Wang ; Weijun Pang ; Gongshe Yang ; gsyang999@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Intramuscular preadipocyte ; MAT2B ; Differentiation ; SAMe ; AKT/ERK ; Pig
- 刊名：Experimental Cell Research
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：344
- 期：1
- 页码：11-21
- 全文大小：4513 K
文摘
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MAT2B up-regulates the expression of adipogenic marker genes and promotes porcine intramuscular preadipocyte differentiation.
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MAT2B influences intracellular SAMe levels and further affects cell clonal expansion.
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MAT2B interacts with AKT and activates AKT/ERK signaling pathway.