E6D25E, HPV16 Asian variant shows specific proteomic pattern correlating in cells transformation and suppressive innate immune response
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- 作者：Peechanika Chopjitta ; e ; Chamsai Pientonga ; e ; Nuchsupha Sunthamalaa ; e ; Bunkerd Kongyingyoesb ; Ornuma Haononc ; Thidarut Boonmarsc ; Satomi Kikawad ; Tomomi Nakaharad ; Tohru Kiyonod ; tkiyono@ncc.go.jp" class="auth_mail" title="E-mail the corresponding author ; Tipaya Ekalaksananana ; e ; tipeka@kku.ac.th" class="auth_mail" title="E-mail the corresponding author
- 关键词：E6Pro ; E6D25E ; HPV16As variant ; Human cervical keratinocyte (HCK1T) ; Protein profile ; gp96 (HSP90B1)
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：9 September 2016
- 年：2016
- 卷：478
- 期：1
- 页码：417-423
- 全文大小：1570 K
文摘
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E6D25E HPV16 specifically modulates protein profile of human keratinocytes.
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E6D25E HPV16 modulates protein profile which involves in TLR signalling and transformation of squamocolumnar junction cells.
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E6D25E oncoprotein may correlate to impair of immune response against viral infection and cells transformation.