Highly active rhodium/phosphorus catalytic system for the hydroformylation of α-methylstyrene

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• 作者：Xue-Li Zheng^a ; ^{zhengxueli@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Cong-Ye Zheng^a ; Fan-Ding Zhou^a ; Hai-Yan Fu^a ; Mao-Lin Yuan^a ; Rui-Xiang Li^a ; Bin Xu^b ; Hua Chen^a ; ^{scuhchen@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：α-Methylstyrene ; Hydroformylation ; Rh complex ; Phosphine ; Pyrrole
• 刊名：Chinese Chemical Letters
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：27
• 期：5
• 页码：678-680
• 全文大小：276 K

文摘

Rhodium catalyzed hydroformylation of α-methylstyrene was investigated in the presence of monodentate phosphine ligands L1–L6. We found that the phosphine with good π-acceptability could efficiently improve the activity of the α-methylstyrene hydroformylation. The big steric hindrance of α-C in α-methylstyrene enhanced the regioselectivity towards the linear aldehyde, which resulted in 3-phenylbutanal as the predominant product (>99.0%). When tris(N-pyrrolyl)phosphine (L1) modified Rh(acac)(CO)₂ was employed as the catalyst, the TOF could reach up to 5786 h⁻¹ in the α-methylstyrene hydroformylation at relatively mild conditions (110 °C, 6 MPa).