Preferential development of neuropeptide Y/GABA circuit in hypothalamic arcuate nucleus in postnatal rats
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- 作者：Xiaoping Suna ; b ; Tatsuya Fukamia ; Tie Lia ; Mina Desaia ; b ; Michael G. Rossa ; b ; Mikeross@ucla.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：ARH ; Arcuate nucleus of hypothalamus ; NPY ; neuropeptide Y ; POMC ; proopiomelanocortin ; αMSH ; α-Melanocyte stimulating hormone ; IHC ; immunohistochemistry ; sc rtPCR ; single cell reverse transcriptase polymerase chain reaction ; sPSC ; spontaneous postsynaptic current ; sIPSC ; spontaneous inhibitory postsynaptic current ; sEPSC ; spontaneous excitatory postsynaptic current ; AP ; action potential
- 刊名：Brain Research
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：1635
- 期：Complete
- 页码：27-40
- 全文大小：6991 K
文摘
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We examined postnatal arcuate nucleus development.
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The density of NPY fibers increases after the second postnatal week.
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NPY and POMC fibers are mutually juxtaposed to perikarya of both neurons.
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Spontaneous inhibitory and excitatory postsynaptic currents increase with age.
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The ARH neural circuit undergoes significant development during the postnatal period.