Group G streptococcal endocarditis-associated hemophagocytic syndrome

详细信息    查看全文

• 作者：Mohammad Naffaa ; Janan Awad ; Ilana Oren ; Eyal Braun ; Noa Lavi
• 关键词：Group G streptococci ; Infective endocarditis ; Hemophagocytic syndrome
• 刊名：International Journal of Infectious Diseases
• 出版年：December, 2013
• 年：2013
• 卷：17
• 期：12
• 页码：e1237-e1239
• 全文大小：769 K

文摘

| Figures/TablesFigures/Tables | ReferencesReferences

Summary

We report the case of a 28-year-old previously healthy male who presented with a 1-week history of fever, headache, vomiting, and jaundice. Blood cultures were positive for group G streptococci and transesophageal echocardiography demonstrated vegetations on the aortic valve, leading to a definitive diagnosis of infective endocarditis. The combination of fever, splenomegaly, anemia, thrombocytopenia, hypertriglyceridemia, elevated ferritin level, low natural killer (NK) cell activity, and hemophagocytosis in bone marrow aspirate confirmed the diagnosis of hemophagocytic syndrome (hemophagocytic lymphohistiocytosis). Antibiotic treatment and intravenous immunoglobulins were administered and the patient made a full recovery.