Complications after surgery for metastatic humeral lesions

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• 作者：Stein J. Janssen ; MD^a ; ^{steinjanssen@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Maarten van Dijke ; BSc^a ; Santiago A. Lozano-Calderó ; n ; MD ; PhD^a ; John E. Ready ; MD^b ; Kevin A. Raskin ; MD^a ; Marco L. Ferrone ; MD^b ; Francis J. Hornicek ; MD ; MS ; PhD^a ; Joseph H. Schwab ; MD ; MS^a
• 关键词：Level III ; Case Series ; Treatment Study
• 刊名：Journal of Shoulder and Elbow Surgery
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：25
• 期：2
• 页码：207-215
• 全文大小：619 K

文摘

Knowledge of surgical outcome and its predictors helps inform patients and aids in surgical decision-making. We aimed to assess the outcome—reoperation and systemic complication rate—of surgery for humeral metastases, myeloma, or lymphoma. Our null hypothesis was that there are no factors associated with these outcomes.

Methods

We included 295 consecutive patients in this retrospective study: 134 (45%) proximal, 131 (44%) diaphyseal, and 30 (10%) distal impending or pathologic fractures. Proximal lesions were treated by intramedullary nailing (43%, n = 57), prosthesis (34%, n = 46), plate-screw fixation (22%, n = 30), and a combination (n = 1). Diaphyseal lesions were treated by intramedullary nailing (69%, n = 91), plate-screw fixation (30%, n = 39), and a combination (n = 1). Distal lesions were treated by plate-screw fixation (97%, n = 29) and intramedullary nailing (3.3%, n = 1).

Results

We found 25 (8.5%) reoperations, and 17 (5.8%) patients had 18 systemic complications: pneumonia (3.7%, n = 11), pulmonary embolism (1.3%, n = 4), sepsis (0.68%, n = 2), and fat embolism (0.34%, n = 1). No factors were independently associated with reoperation. Logistic regression analysis demonstrated that favorable cancer status (i.e., a higher modified Bauer score: odds ratio, 0.48; 95% confidence interval, 0.29-0.80; P = .005) was independently associated with a decreased systemic complication rate.

Conclusion

Poor cancer status was an independent predictor of postoperative systemic complications. This could help inform the patient and anticipate postoperative problems.