Differential mechanistic investigation of protective effects from imperatorin and sec-O-glucosylhamaudol against arsenic trioxide-induced cytotoxicity in vitro
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- 作者：Liufang Hu cacms2014@163.com" class="auth_mail" title="E-mail the corresponding author ; Jianhui Sun sjh121858@sina.com" class="auth_mail" title="E-mail the corresponding author ; Hongmei Li sinomd@sina.com" class="auth_mail" title="E-mail the corresponding author ; Lifang Wang wanglifang73@163.com" class="auth_mail" title="E-mail the corresponding author ; Yuna Wei weiyuna0914@163.com" class="auth_mail" title="E-mail the corresponding author ; Ying Wang 15189802005@163.com" class="auth_mail" title="E-mail the corresponding author ; Yaying Zhu zhuysml75@sina.com" class="auth_mail" title="E-mail the corresponding author ; Hairu Huo hrhuo@sohu.com" class="auth_mail" title="E-mail the corresponding author ; Yuqing Tan ; yqtan@icmm.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：As2O3-induced cytotoxicity ; Imperatorin ; sec-O-glucosylhamaudol ; Mechanisms
- 刊名：Toxicology in Vitro
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：37
- 期：Complete
- 页码：97-105
- 全文大小：1272 K
文摘
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The new pharmacological action of traditional Chinese medicine Radix Saposhnikoviae
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Imperatorin can ameliorate As2O3-induced cytotoxicity and apoptosis in H9c2 cells.
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sec-O-glucosylhamaudol can ameliorate As2O3-induced cytotoxicity and apoptosis in H9c2 cells.
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A novel strategy to expand the clinical application of As2O3