[KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis
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- 作者：Genjiro Suzuki1 ; Jonathan S. Weissman2 ; 3 ; 4 ; Motomasa Tanaka1 ; motomasa@brain.riken.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2015
- 出版时间：19 November 2015
- 年：2015
- 卷：60
- 期：4
- 页码：651-660
- 全文大小：2350 K
文摘
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[KIL-d] is a proteinaceous prion-like aggregate
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[KIL-d] increases the rate of de novo mutation in the killer viral genome
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A prion-like [KIL-d] element induces viral inactivation via the “error catastrophe”
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Prion-like protein aggregates play roles in cellular defense and adaptation