Additive effect of harmane and muscimol for memory consolidation impairment in inhibitory avoidance task
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- 作者：Mohammad Nasehia ; Nasehi@iricss.org" class="auth_mail" title="E-mail the corresponding author ; Parastoo Morteza-zadehb ; Fatemeh Khakpaic ; Mohammad-Reza Zarrindasta ; c ; d ; e ; f ; g ; Zarinmr@ams.ac.ir" class="auth_mail" title="E-mail the corresponding author
- 关键词：harmane ; GABAA receptor ; the CA1 area ; step-down passive avoidance ; memory
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：17 December 2016
- 年：2016
- 卷：339
- 期：Complete
- 页码：287-295
- 全文大小：634 K
文摘
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Post-training infusion of bicuculline did not alter but muscimol impaired memory.
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I.p. injection of harmane impaired memory consolidation.
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Bicuculline decreased, but muscimol increased amnesia induced by harmane.
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There is an additive effect among harmane and muscimol on impairment of memory.
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GABAergic system of the CA1 may modulate harmane-induced amnesia.