Determination of salivary cotinine through solid phase extraction using a bead-injection lab-on-valve approach hyphenated to hydrophilic interaction liquid chromatography
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- 作者：Adlin N. Ramdzana ; Luí ; sa Barreirosb ; M. Inê ; s G.S. Almeidaa ; Spas D. Koleva ; Marcela A. Segundob ; msegundo@ff.up.pt" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cotinine ; Saliva ; Hydrophilic interaction liquid chromatography ; Bead injection ; Lab-on-valve
- 刊名：Journal of Chromatography A
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：1429
- 期：Complete
- 页码：284-291
- 全文大小：599 K
文摘
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Non-invasive determination of salivary cotinine to assess tobacco smoke exposure.
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At-line coupling of reversed phase SPE to HILIC resulted in high compatibility.
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Minimal solvent usage/wastage due to full automation of reversed-phase micro-SPE.