Treatment of autistic spectrum disorder with insulin-like growth factors
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- 作者：Raili Riikonen ; raili.riikonen@kolumbus.fi" class="auth_mail" title="E-mail the corresponding author
- 关键词：Autism-spectrum disorder ; Insulin-like growth factor ; Therapy
- 刊名：European Journal of Paediatric Neurology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：20
- 期：6
- 页码：816-823
- 全文大小：340 K
文摘
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In autistic spectrum disorder (ASD) there are dysregulated synapses.
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There is now more knowledge on emerging mechanisms and mechanism-based therapies.
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Insulin-like growth factor (IGF-1) is altered in autism.
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IGF-1 may rescue function in Rett syndrome and in SCHANK3 gene deficiency syndrome.
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There are now pilot studies of treatment of ASD.