- 作者：Silvio Romero de Barros-Marques ; PhD ; Esdras Marques-Lins ; PhD ; esdraslins@uol.com.br ; Maria Clá ; udia Sodré ; de Albuquerque ; PhD ; José ; Lamartine de Andrade-Aguiar ; PhD
- 刊名：Journal of Vascular Surgery
- 出版年：2012
- 出版时间：February 2012
- 年：2012
- 卷：55
- 期：2
- 页码：517-521
- 全文大小：1411 K
class=""h4"">Purpose
To evaluate the use of the sugarcane biopolymer membrane in femoral vein patch angioplasty on dogs.class=""h4"">Methods
Eight dogs were submitted to bilateral femoral vein patch angioplasty with a sugarcane biopolymer membrane patch on one side and an expanded polytetrafluoroethylene (e-PTFE) patch on the contralateral side. This research was performed at Experimental Surgical Research Laboratory of the Centro de Ci¨ºncias da Sa¨²de at Universidade Federal de Pernambuco. The dogs underwent new surgery at 180 days after the patch angioplasty in order to harvest the femoral vein. All the animals were evaluated by clinical examination, measure of femoral vein diameter, venogram, and Doppler fluxometry. The material harvested was sent for histologic study. Each animal served as its own control.
class=""h4"">Results
In all veins of both groups, there were no cases of infection, rupture, or pseudoaneurysm formation and thrombosis. In both groups, a chronic inflammatory reaction was observed, with lymphocytes, neutrophils, and fibrosis in the outer surface of the patches. Fibrosis was seen in the inner surfaces of all the patches. In e-PTFE patches, invasion by fibroblasts occurred.
class=""h4"">Conclusions
The sugarcane biopolymer membrane can be used as a patch in femoral vein angioplasty on dogs.