What is the evidence for metabolic surgery for type 2 diabetes? A critical perspective

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• 作者：C. Amouyal ; F. Andreelli ; ^{fabrizio.andreelli@psl.aphp.fr}
• 关键词：Bariatric surgery ; Metabolic surgery ; Obesity ; Type 2 diabetes
• 刊名：Diabetes & Metabolism
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：43
• 期：1
• 页码：9-17
• 全文大小：722 K
• 卷排序：43

文摘

Bariatric surgery has emerged as a highly effective treatment not only for obesity, but also for type 2 diabetes (T2D). A meta-analysis has reported the complete resolution of T2D in 78.1% of cases of morbidly obese patients after bariatric surgery. Such extraordinary results obtained in diabetic patients with body mass index (BMI) scores > 35 kg/m2 have led investigators to question whether similar results might be achieved in patients with BMIs < 35 kg/m2. Preliminary studies suggest that metabolic surgery is safe and effective in patients with T2D and a BMI < 35 kg/m2, whereas other studies report that metabolic surgery is less effective for promoting T2D remission in these patients. Thus, the results are discordant. Long-term studies would be useful for determining the safety, efficacy and cost-effectiveness of metabolic surgery for this population with T2D. In 2015, it is probably premature to say that metabolic surgery is an accepted treatment option for T2D patients with BMIs < 35 kg/m2.