OXA-23 and ISAba1-OXA-66 class D β-lactamases in Acinetobacter baumannii isolates from companion animals

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• 作者：Christa Ewers^a ; ^{christa.ewers@vetmed.uni-giessen.de} ; Peter Klotz^a ; Ursula Leidner^a ; Ivonne Stamm^b ; Ellen Prenger-Berninghoff^a ; Stephan Gö ; ttig^c ; Torsten Semmler^d ; Sandra Scheufen^a
• 关键词：Acinetobacter ; Carbapenems ; OXA ; ISAba1 ; Tn2008 ; Animal
• 刊名：International Journal of Antimicrobial Agents
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：49
• 期：1
• 页码：37-44
• 全文大小：1631 K
• 卷排序：49

文摘

OXA-23 carbapenemase on transposon Tn2008 is found in Acinetobacter baumannii isolates from dogs. A. baumannii international clones IC1 and IC2 are emerging in dogs and cats. OXA-66 β-lactamase with upstream ISAba1 is frequently detected in IC2 isolates of dogs/cats. A. baumannii appears to be a nosocomial pathogen in veterinary clinics. Animal A. baumannii share resistance determinants and clonal lineages with human isolates.