• 作者：Ignacio Herraiz Garcí ; a^a ; Ana Elena L&#243 ; pez Jimé ; nez^b ; Paula Isabel G&#243 ; mez Arriaga^a ; David Escribano Abad^a ; Alberto Galindo Izquierdo^a ; ^{agalindo.hdoc@salud.madrid.org}
• 关键词：Preeclampsia ; Factores angiogé ; nicos ; Arterias uterinas ; Predicció ; n ; Diagnó ; stico
• 刊名：Diagn¨®stico Prenatal
• 出版年：2011
• 出版时间：April-June 2011
• 年：2011
• 卷：22
• 期：2
• 页码：32-40
• 全文大小：369 K

Pre-eclampsia remains a principal cause of maternal and perinatal morbidity and mortality. Despite its repercussions, so far there have been no methods for early diagnosis and prevention of complications. Selection strategies based on the presence of maternal risk factors are not efficient. The use of uterine artery Doppler has not been accepted in routine practice, but in combination with new angiogenic markers sFlt-1 and PlGF it becomes a very powerful tool for the prediction and early diagnosis of pre-eclampsia.

This article will discuss the challenge of transferring the study of uterine artery Doppler and angiogenic markers sFlt-1 and PlGF to daily clinical practice in the light of the available data from recent studies.