Prolonged maternal separation induces undernutrition and systemic inflammation with disrupted hippocampal development in mice
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- 作者：Í ; talo Leite Figueiredo ; D.V.M. ; Ph.D.a ; Priscila B. Frota ; M.D.a ; Davi G. da Cunha ; M.Sc.a ; Ramon da Silva Raposo ; D.V.M. ; Ph.D.h ; Kildere M. Canuto ; M.Sc.a ; Geanne M. de Andrade ; Ph.D.b ; Nuno Sousa ; M.D. ; Ph.D.c ; d ; Sean R. Moore ; M.D. ; Ph.D.i ; Gregory M. Anstead ; M.D.f ; Jacqueline I. Alvarez-Leite ; M.D. ; Ph.D.e ; Richard L. Guerrant ; M.D.g ; Reinaldo B. Oriá ; D.V.M. ; Ph.D.a ; rbo5u@virginia.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Maternal separation ; Malnutrition ; Hippocampus ; Stereology ; Leptin ; IGF-1 ; Inflammation
- 刊名：Nutrition
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：32
- 期：9
- 页码：1019-1027
- 全文大小：672 K
文摘
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Prolonged maternal separation induces systemic inflammation.
Prolonged maternal separation affects insulin-like growth factor-1 serum levels and growth.
Prolonged maternal separation delays neonatal reflex development.
Prolonged maternal separation affects hippocampal morphology and amino acid levels.