A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity
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- 作者：Ana C. D&rsquo ; Alessio1 ; 7 ; Zi Peng Fan1 ; 2 ; 7 ; Katherine J. Wert1 ; Petr Baranov3 ; Malkiel A. Cohen1 ; Janmeet S. Saini4 ; 5 ; Evan Cohick1 ; Carol Charniga4 ; Daniel Dadon1 ; 6 ; Nancy M. Hannett1 ; Michael J. Young3 ; Sally Temple4 ; Rudolf Jaenisch1 ; 6 ; Tong Ihn Lee1 ; tlee@wi.mit.edu" class="auth_mail" title="E-mail the corresponding author ; Richard A. Young1 ; 6 ; young@wi.mit.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Stem Cell Reports
- 出版年：2015
- 出版时间：10 November 2015
- 年：2015
- 卷：5
- 期：5
- 页码：763-775
- 全文大小：5192 K
文摘
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Core transcription factors (TFs) are predicted for >200 cell types/tissues
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Predicted TFs for retinal pigment epithelial (RPE) cells can reprogram fibroblasts
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These reprogrammed RPE-like cells are functionally similar to primary RPE
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The sets of predicted factors may facilitate studies of control of cell identity