Development and validation of a metal mixture bioavailability model (MMBM) to predict chronic toxicity of Ni-Zn-Pb mixtures to Ceriodaphnia dubia

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• 作者：Charlotte Nys ; ^{chnys.nys@ugent.be} ; Colin R. Janssen ^{colin.janssen@ugent.be} ; Karel A.C. De Schamphelaere ^{karel.deschamphelaere@ugent.be}
• 关键词：Metals ; Mixture toxicity ; Biotic ligand model ; Risk assessment ; Freshwater
• 刊名：Environmental Pollution
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：220
• 期：part_PB
• 页码：1271-1281
• 全文大小：1018 K
• 卷排序：220

文摘

Chronic Ni-Zn-Pb toxicity to C. dubia is most accurately predicted by the independent action model. The concentration addition model results in the most conservative predictions. Interactive effects are dependent on the metal concentration ratio investigated. A metal mixture bioavailability model (MMBM) for chronic toxicity was developed. The MMBM can account for the effects of water chemistry on Ni-Zn-Pb mixture toxicity.