- 作者：Michael S. Schechter ; MD ; MPH<sup>asup><sup> ; sup><sup>Michael.Schechter@emory.edusup> ; Susanna A. McColley ; MD<sup>bsup> ; Warren Regelmann ; MD<sup>csup> ; Stefanie J. Millar ; MS<sup>dsup> ; David J. Pasta ; MS<sup>dsup> ; Jeffrey S. Wagener ; MD<sup>esup> ; Michael W. Konstan ; MD<sup>fsup> ; Wayne J. Morgan ; MD<sup>gsup> ; Investigators ; Coordinators of the Epidemiologic Study of Cystic Fibrosis &lowast
- 关键词：CF ; Cystic fibrosis ; ESCF ; Epidemiologic Study of Cystic Fibrosis ; FEV1 ; Forced expiratory volume in 1 second ; IV ; Intravenous ; MA ; Medicaid or state insurance ; MEA ; Maternal educational attainment ; MIZ ; Median household income by zip code ; SES ; Socioecon
- 刊名：The Journal of Pediatrics
- 出版年：2011
- 出版时间：November, 2011
- 年：2011
- 卷：159
- 期：5
- 页码：819-824.e1
- 全文大小：138 K
ss=""h4"">Objective
To determine whether socioeconomic status (SES) influences the likelihood of antibiotic treatment of pulmonary exacerbations in patients with cystic fibrosis (CF).ss=""h4"">Study design
We used data on 9895 patients ¡Ü18 years old from the Epidemiologic Study of CF. After establishing an individual baseline of clinical signs and symptoms, we ascertained whether antibiotics were prescribed when new signs/symptoms suggested a pulmonary exacerbation, adjusting for sex, presence of Pseudomonas aeruginosa, the number of new signs/symptoms, and baseline disease severity.
ss=""h4"">Results
In a 12-month period, 20.0 % of patients <6 years of age, 33.8 % of patients 6 to 12 years of age, and 41.4 % of patients 13 to 18 years of age were treated with any (oral, intravenous (IV), or inhaled) antibiotics; the percentage receiving IV antibiotics was 7.3 % , 15.2 % , and 20.9 % , respectively. SES had little effect on treatment for pulmonary exacerbation with any antibiotics, but IV antibiotics were prescribed more frequently for patients with lower SES.
ss=""h4"">Conclusions
SES-related disparities in CF health outcomes do not appear to be explained by differential treatment of pulmonary exacerbations.