Gamma rays induce DNA damage and oxidative stress associated with impaired growth and reproduction in the copepod Tigriopus japonicus
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- 作者：Jeonghoon Hana ; 1 ; Eun-Ji Wona ; 1 ; Bo-Young Leea ; Un-Ki Hwangb ; Il-Chan Kimc ; Joung Han Yimc ; Kenneth Mei Yee Leungd ; Yong Sung Leee ; Jae-Seong Leea ; jslee2@skku.edu" class="auth_mail
- 关键词：Gamma rays ; DNA repair ; Oxidative stress ; In vivo endpoints ; Copepod ; Tigriopus japonicus
- 刊名：Aquatic Toxicology
- 出版年：July 2014
- 年：2014
- 卷：152
- 期：Complete
- 页码：264-272
- 全文大小：906 K
文摘
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Mortality rate was significantly increased in response to gamma radiation.
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A dose-dependent reduction in fecundity of ovigerous females.
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Growth retardation, particularly at the nauplius stage.
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Upon gamma radiation, T. japonicus showed an increased ROS levels.
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Antioxidant genes and Hsps genes were upregulated at sublethal doses.