Human cytomegalovirus (HCMV)-seropositive (IgG-positive/IgM-negative) hematopoietic stem cell transplantation recipients exhibited a high rate of herpesvirus infections, particularly Epstein–Barr virus (EBV).
Anti-thymocyte globulin and male sex were strongly associated with an increased risk of EBV infection.
Graft-versus-host disease prophylaxis with prednisone was determined to affect both EBV and HCMV infections.
Prior infection with EBV was shown to promote human herpes virus type 6 infection.