Beneficial effects of urine-derived stem cells on fibrosis and apoptosis of myocardial, glomerular and bladder cells
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- 作者：Xingyou Donga ; Teng Zhanga ; Qian Liua ; Jingzhen Zhua ; Jiang Zhaoa ; Jia Lia ; Bishao Suna ; Guolin Dinga ; Xiaoyan Hua ; Zhenxing Yanga ; Yuanyuan Zhangb ; Longkun Lia ; lilongk@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Diabetes mellitus ; Urine-derived stem cell ; Diabetic cardiomyopathy ; Diabetic nephropathy ; Diabetic cystopathy ; Apoptosis ; Fibrosis
- 刊名：Molecular and Cellular Endocrinology
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：427
- 期：Complete
- 页码：21-32
- 全文大小：4813 K
文摘
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This is the first study to investigate the therapeutic effects of USCs on T2D rats. .
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Injected USCs can differentiate into PDX1-positive cells in rat pancreas.
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Ameliorating the fibrosis and inhibiting cell apoptosis is the possible pathway for the treatment of complications.
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USCs are good resource for the treatment of diabetes mellitus and diabetic complications.